Home Contact Us
Loading

The American Association of Immunologists



1953

Kathryn J. Wood, Andrew R. Bushell, and Nick D. Jones

The Discovery of Immunological Tolerance: Now More Than Just a Laboratory Solution

J Immunol 2010 184: 3-4 [Full Text] [PDF]

R. E. Billingham, L. Brent, and P. B. Medawar

Pillars Article: ‘Actively Acquired Tolerance’ of Foreign Cells. Nature. 1953. 172: 603–606

J Immunol 2010 184: 5-8 [PDF]


1957

Robert Winchester

A Golden Anniversary: Recognition That Rheumatoid Arthritis Sera Contain Autoantibodies Specific for Determinants on Native IgG Molecules

J Immunol 2007 178: 1227-1228 [Full Text] [PDF]

Edward C. Franklin, Halsted R. Holman, Hans J. Muller-Eberhard, and Henry G. Kunkel

Pillars Article: An Unusual Protein Component of High Molecular Weight in the Serum of Certain Patients with Rheumatoid Arthritis. J. Exp. Med. 1957. 105: 425–438

J Immunol 2007 178: 1229-1242 [PDF]


1958

Christophe Viret and Werner Gurr

The Origin of the "One Cell-One Antibody" Rule

J Immunol 2009 182: 1229-1230 [Full Text] [PDF]

G. J. V. Nossal and Joshua Lederberg

Pillars Article: Antibody Production by Single Cells. Nature. 1958. 181: 1419–1420

J Immunol 2009 182: 1231-1232 [PDF]


1966

Carol F. Webb and Paul W. Kincade

The Divergence of Lymphocyte Development Pathways

J Immunol 2006 176: 6369-6369 [Full Text] [PDF]

Max D. Cooper, Raymond D. A. Peterson, Mary Ann South, and Robert A. Good

Pillars Article: The Functions of the Thymus System and the Bursa System in the Chicken. J. Exp. Med. 1966. 123: 75–102

J Immunol 2006 176: 6370-6404 [PDF]


George C. Tsokos

In the Beginning Was Sm

J Immunol 2006 176: 1295-1296 [Full Text] [PDF]

E. M. Tan and H. G. Kunkel

Pillars Article: Characteristics of a Soluble Nuclear Antigen Precipitating with Sera of Patients with Systemic Lupus Erythematosus. J. Immunol. 1966. 96: 464–471

J Immunol 2006 176: 1297-1304 [PDF]


Patricia J. Gearhart

Antibody Wars: Extreme Diversity

J Immunol 2006 177: 4235-4236 [Full Text] [PDF]

Sydney Brenner and César Milstein

Pillars Article: Origin of Antibody Variation. Nature. 1966. 211: 242–243

J Immunol 2006 177: 4237-4238 [PDF]


Jonathan S. Bromberg

The Beginnings of T-B Collaboration

J Immunol 2004 173: 7-8 [Full Text] [PDF]

Henry N. Claman, Edward A. Chaperon, and R. Faser Triplett

Pillars Article: Immunocompetence of Transferred Thymus-Marrow Cell Combinations. J. Immunol. 1966. 97:828-832

J Immunol 2004 173: 9-13 [PDF]


1967

Jeffrey L. Platt

Allophenic Mice: A Pillar Awaiting Its Superstructure

J Immunol 2007 178: 4005-4006 [Full Text] [PDF]

Beatrice Mintz and Willys K. Silvers

Pillars Article: "Intrinsic" Immunological Tolerance in Allophenic Mice. Science. 1967. 158: 1484–1487

J Immunol 2007 178: 4007-4010 [PDF]


1969

Jack R. Bennink

Making the Connection: Antibody Responsiveness and MHC Genes

J Immunol 2004 173: 1499-1499 [Full Text] [PDF]

Hugh O. McDevitt and Allen Chinitz

Pillars Article: Genetic Control of the Antibody Responses: Relationship between Immune Response and Histocompatibility (H-2) Type. Science. 1969. 163:1207–1208

J Immunol 2004 173: 1500-1501[PDF]


Norman R. Klinman

When Two-Dimensional Structure Led the Way

J Immunol 2004 173: 5333-5334 [Full Text] [PDF]

Gerald M. Edelman, Bruce A. Cunningham, W. Einar Gall, Paul D. Gottlieb, Urs Rutishauser, and Myron J. Waxdal

Pillars Article: The Covalent Structure of an Entire γG Immunoglobulin Molecule. Proc. Natl. Acad. Sci. USA. 1969. 63: 78–85

J Immunol 2004 173: 5335-5342 [PDF]


Pamela J. Fink

More Than Just Vanilla

J Immunol 2008 180: 4351-4352 [Full Text] [PDF]

Martin C. Raff

Pillars Article: Theta Isoantigen as a Marker of Thymus-Derived Lymphocytes in Mice. Nature. 1969. 224: 378–379

J Immunol 2008 180: 4353-4354 [PDF]


1970

Leroy E. Hood

Wu and Kabat 1970: A Transforming View of Antibody Diversity

J Immunol 2008 180: 7055-7056 [Full Text] [PDF]

Tai Te Wu and Elvin A. Kabat

Pillars Article: An Analysis of the Sequences of the Variable Regions of Bence Jones Proteins and Myeloma Light Chains and their Implications for Antibody Complementarity. J. Exp. Med. 1970. 132: 211–250

J Immunol 2008 180: 7057-7096 [PDF]


1971

Pamela J. Fink

T Cells Stop to Smell the (Antigenic) Roses

J Immunol 2006 177: 1379-1380 [Full Text] [PDF]

Jonathan Sprent, Jacques F. A. P. Miller, and Graham F. Mitchell

Pillars Article: Antigen-Induced Selective Recruitment of Circulating Lymphocytes. Cell. Immunol. 1971. 2: 171–181

J Immunol 2006 177: 1381-1391 [PDF]


Jiri Mestecky and Charles O. Elson

Peyer’s Patches as the Inductive Site for IgA Responses

J Immunol 2008 180: 1293-1294 [Full Text] [PDF]

Susan W. Craig and John J. Cebra

Pillars Article: Peyer’sPatches: An Enriched Source of Precursors for IgA-Producing Immunocytes in the Rabbit. J. Exp. Med. 1971. 134: 188–200

J Immunol 2008 180: 1295-1307 [PDF]


1972

Michael P. Cancro

Crossing the Threshold of Lymphocyte Activation

J Immunol 2005 174: 5159-5160 [Full Text] [PDF]

Norman R. Klinman

Pillars Article: The Mechanism of Antigenic Stimulation of Primary and Secondary Clonal Precursor Cells. J. Exp. Med. 1972. 136: 241–260

J Immunol 2005 174: 5161-5180 [PDF]


Michael R. Blackburn and Linda F. Thompson

Adenosine Deaminase Deficiency: Unanticipated Benefits from the Study of a Rare Immunodeficiency

J Immunol 2012 188: 933-935 [Full Text] [PDF]

Eloise R. Giblett, Jeanne E. Anderson, Flossie Cohen, Bernard Pollara, and Hilaire J. Meuwissen

Pillars Article: Adenosine-Deaminase Deficiency in Two Patients with Severely Impaired Cellular Immunity. The Lancet. 1972. 300: 1067–1069

J Immunol 2012 188: 936-938 [PDF]


1973

Giorgio Trinchieri

The Birth of a Cell Type

J Immunol 2007 178: 3-4 [Full Text] [PDF]

Ralph M. Steinman and Zanvil A. Cohn

Pillars Article: Identification of a Novel Cell Type in Peripheral Lymphoid Organs of Mice. I. Morphology, Quantitation, Tissue Distribution. J. Exp. Med. 1973. 137: 1142–1162

J Immunol 2007 178: 5-25 [PDF]


Ted H. Hansen

Which Lymphoid Cells Express MHC Class II Antigens; Are TCRs Encoded within the MHC?

J Immunol 2011 187: 2043-2044 [Full Text] [PDF]

David H. Sachs and James L. Cone

Pillars Article: A Mouse B-Cell Alloantigen Determined By Gene(s) Linked To The Major Histocompatibility Complex. J. Exp. Med. 1973. 138: 1289–1304

J Immunol 2011 187: 2045-2060 [PDF]


1974

Michael J. Bevan

Altered Self, Altered World

J Immunol 2004 173: 2897-2898 [Full Text] [PDF]

Rolf M. Zinkernagel and Peter C. Doherty

Pillars Article: Immunological Surveillance against Altered Self Components by Sensitised T Lymphocytes in Lymphocytic Choriomeningitis. Nature. 1974. 251: 547–548

J Immunol 2004 173: 2899-2900 [PDF]


1975

Christopher C. Goodnow

Nossal and Pike 1975: A Turning Point in the Effort to Define Self-Tolerance Mechanisms

J Immunol 2007 179: 5617-5618 [Full Text] [PDF]

G. J. V. Nossal and Beverley L. Pike

Pillars Article: Evidence for the Clonal Abortion Theory of B-Lymphocyte Tolerance. J. Exp. Med. 1975. 141: 904–917

J Immunol 2007 179: 5619-5632 [PDF]


Leonard Chess

The Birth of Functionally Distinct T Cell Subsets

J Immunol 2006 176: 3859-3860 [Full Text] [PDF]

H. Cantor and E. A. Boyse

Pillars Article: Functional Subclasses of T Lymphocytes Bearing Different Ly Antigens. I. The Generation of Functionally Distinct T-Cell Subclasses is a Differentiative Process Independent of Antigen. J. Exp. Med. 1975. 141: 1376–1389

J Immunol 2006 176: 3861-3874 [PDF]


David H. Margulies

Monoclonal Antibodies: Producing Magic Bullets by Somatic Cell Hybridization

J Immunol 2005 174: 2451-2452 [Full Text] [PDF]

G. Köhler and C. Milstein

Pillars Article: Continuous Cultures of Fused Cells Secreting Antibody of Predefined Specificity. Nature. 1975. 256: 495–497

J Immunol 2005 174: 2453-2455 [PDF]


Harald von Boehmer

Shaping the T Cell Repertoire

J Immunol 2005 175: 7067-7068 [Full Text] [PDF]

Michael John Bevan

Pillars Article: The Major Histocompatibility Complex Determines Susceptibility to Cytotoxic T Cells Directed against Minor Histocompatibility Antigens. J. Exp. Med. 1975. 142: 1349–1364

J Immunol 2005 175: 7069-7084 [PDF]


1976

Graham Anderson and Eric J. Jenkinson

Bringing the Thymus to the Bench

J Immunol 2008 181: 7435-7436 [Full Text] [PDF]

J. H. Robinson and J. J. T. Owen

Pillars Article: Generation of T-cell Function in Organ Culture of Foetal Mouse Thymus. I. Mitogen Responsiveness. Clin. Exper. Immunol. 1976. 23: 347–354

J Immunol 2008 181: 7437-7444 [PDF]


Patricia J. Gearhart

The Birth of Molecular Immunology

J Immunol 2004 173: 4259-4259 [Full Text] [PDF]

N. Hozumi and S. Tonegawa

Pillars Article: Evidence for Somatic Rearrangement of Immunoglobulin Genes Coding for Variable and Constant Regions. Proc. Natl. Acad. Sci. USA. 1976. 73: 3628-3632

J Immunol 2004 173: 4260-4264 [PDF]


Francis R. Carbone and William R. Heath

Cross-Priming: Its Beginnings

J Immunol 2010 185: 1353-1354 [Full Text] [PDF]

Michael J. Bevan

Pillars Article: Minor H Antigens Introduced on H-2 Different Stimulating Cells Cross-React at the Cytotoxic T Cell Level during In Vivo Priming. J. Immunol. 1976. 117: 2233–2238

J Immunol 2010 185: 1355-1360 [PDF]

Michael J. Bevan

Pillars Article: Cross-Priming for a Secondary Cytotoxic Response to Minor H Antigens with H-2 Congenic Cells Which Do Not Cross-React in the Cytotoxic Assay. J. Exp. Med. 1976. 143: 1283–1288

J Immunol 2010 185: 1361-1366 [PDF]


1977

Joost J. Oppenheim

IL-2: More Than a T Cell Growth Factor

J Immunol 2007 179: 1413-1414 [Full Text] [PDF]

Francis W. Ruscetti, Doris A. Morgan, and Robert C. Gallo

Pillars Article: Functional and Morphologic Characterization of Human T Cells Continuously Grown In Vitro. J. Immunol. 1977. 119: 131–138

J Immunol 2007 179: 1415-1422 [PDF]


Harald von Boehmer

Shaping the T Cell Repertoire

J Immunol 2006 176: 3-4 [Full Text][PDF]

Michael J. Bevan

Pillars Article: In a Radiation Chimaera, Host H-2 Antigens Determine Immune Responsiveness of Donor Cytotoxic Cells. Nature. 1977. 269: 417–418

J Immunol 2006 176: 5-6 [PDF]


1980

J. Donald Capra

Multiple Genes, One Polypeptide Chain

J Immunol 2004 173: 6501-6502 [Full Text] [PDF]

P. Early, H. Huang, M. Davis, K. Calame, and L. Hood

Pillars Article: An Immunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA: VH, D and JH. Cell. 1980. 19: 981–992

J Immunol 2004 173: 6503-6514 [PDF]


1981

Jack L. Strominger

Animal Antimicrobial Peptides: Ancient Players in Innate Immunity

J Immunol 2009 182: 6633-6634 [Full Text] [PDF]

Hakan Steiner, Dan Hultmark, Åke Engström, Hans Bennich, and Hans G. Boman

Pillars Article: Sequence and Specificity of Two Antibacterial Proteins Involved in Insect Immunity. Nature. 1981. 292: 246–248

J Immunol 2009 182: 6635-6637 [PDF]


Paul F. Robbins

Helping Tumor Cells To Die

J Immunol 2013 190: 1897-1898 [Full Text][PDF]

Philip D. Greenberg, Martin A. Cheever, and Alexander Fefer

Pillars Article: Eradication of Disseminated Murine Leukemia by Chemoimmunotherapy with Cyclophosphamide and Adoptively Transferred Immune Syngeneic Lyt-1+2 Lymphocytes. J. Exp. Med. 1981. 154: 952–963

J Immunol 2013 190: 1899-1910 [PDF]


Paul M. Allen

Making Antigen Presentable

J Immunol 2007 179: 3-4 [Full Text] [PDF]

Kirk Ziegler and Emil R. Unanue

Pillars Article: Identification of a Macrophage Antigen-Processing Event Required for I-Region-Restricted Antigen Presentation to T Lymphocytes. J. Immunol. 1981. 127: 1869–1875

J Immunol 2007 179: 5-11 [PDF]


1982

Robert L. Coffman

Converging Discoveries: The First Reports of IL-4

J Immunol 2013 190: 847-848 [Full Text][PDF]

Peter C. Isakson, Ellen Pure, Ellen S. Vitetta, and Peter H. Krammer

Pillars Article: T Cell-Derived B Cell Differentiation Factor(s). Effect on the Isotype Switch of Murine B Cells. J. Exp. Med. 1982. 155: 734–748

J Immunol 2013 190: 849-863 [PDF]

Maureen Howard, John Farrar, Mary Hilfiker, Barbara Johnson, Kiyoshi Takatsu, Toshiyuki Hamaoka, and William E. Paul

Pillars Article: Identification of a T Cell-Derived B Cell Growth Factor Distinct from Interleukin 2. J. Exp. Med. 1982. 155: 914–923

J Immunol 2013 190: 864-873 [PDF]


Lewis L. Lanier

First Sighting of the Elusive T Cell Antigen Receptor

J Immunol 2005 174: 1143-1143 [Full Text] [PDF]

James P. Allison, Bradley W. McIntyre, and David Bloch

Pillars Article: Tumor-Specific Antigen of Murine T-Lymphoma Defined with Monoclonal Antibody. J. Immunol. 1982. 129: 2293–2300

J Immunol 2005 174: 1144-1151 [PDF]


Jerry R. McGhee

Peyer’s Patch Germinal Centers: The Elusive Switch Site for IgA

J Immunol 2005 175: 1361-1362 [Full Text] [PDF]

Eugene C. Butcher, Robert V. Rouse, Robert L. Coffman, Carol N. Nottenburg, Richard R. Hardy, and Irving L. Weissman

Pillars Article: Surface Phenotype of Peyer’s Patch Germinal Center Cells: Implications for the Role of Germinal Centers in B Cell Differentiation. J. Immunol. 1982. 129: 2698–2707

J Immunol 2005 175: 1363-1372 [PDF]


1983

Steven D. Rosen

Homing in on L-Selectin

J Immunol 2006 177: 3-4 [Full Text] [PDF]

W. Michael Gallatin, Irving L. Weissman, and Eugene C. Butcher

Pillars Article: A Cell-Surface Molecule Involved in Organ-Specific Homing of Lymphocytes. Nature. 1983. 304: 30–34

J Immunol 2006 177: 5-9 [PDF]


Stephen M. Hedrick

The TCR of Mice and Men

J Immunol 2006 176: 2681-2682 [Full Text] [PDF]

John Kappler, Ralph Kubo, Kathryn Haskins, Charles Hannum, Philippa Marrack, Michele Pigeon, Bradley McIntyre, James Allison, and Ian Trowbridge

Pillars Article: The Major Histocompatibility Complex-restricted Antigen Receptor on T Cells in Mouse and Man: Identification of Constant and Variable Peptides. Cell. 1983. 35: 295–302

J Immunol 2006 176: 2683-2690 [PDF]


1984

Arthur Weiss

Discovering the TCR β-Chain by Subtraction

J Immunol 2005 175: 2769-2770 [Full Text] [PDF]

Stephen M. Hedrick, David I. Cohen, Ellen A. Nielsen, and Mark M. Davis

Pillars Article: Isolation of cDNA Clones Encoding T Cell-Specific Membrane-Associated Proteins. Nature. 1984. 308: 149–153

J Immunol 2005 175: 2771-2775 [PDF]


Marko Radic

Tracking and Trapping Somatic Mutations in Ig Genes

J Immunol 2008 180: 5763-5764 [Full Text] [PDF]

David McKean, KonradHuppi, Michael Bell, Louis Staudt, Walter Gerhard, and Martin Weigert

Pillars Article: Generation of Antibody Diversity in the Immune Response of BALB/c Mice to Influenza Virus Hemagglutinin. Proc. Natl. Acad. Sci. USA. 1984. 81: 3180–3184

J Immunol 2008 180: 5765-5769 [PDF]


Hidde L. Ploegh

Bridging B Cell and T Cell Recognition of Antigen

J Immunol 2007 179: 7193-7193 [Full Text] [PDF]

Kenneth L. Rock, Baruj Benacerraf, and Abul K. Abbas

Pillars Article: Antigen Presentation by Hapten-Specific B Lymphocytes. 1. Role of Surface Immunoglobulin Receptors. J. Exp. Med. 1984. 160: 1102–1113

J Immunol 2007 179: 7194-7205 [PDF]

Antonio Lanzavecchia

Pillars Article: Antigen-Specific Interaction between T and B Cells. Nature. 1985. 314: 537–539

J Immunol 2007 179: 7206-7208 [PDF]


Theresa T. Pizarro and Fabio Cominelli

Cloning IL-1 and the Birth of a New Era in Cytokine Biology

J Immunol 2007 178: 5411-5412 [Full Text] [PDF]

Philip E. Auron, Andrew C. Webb, Lanny J. Rosenwasser, Steven F. Mucci, Alexander Rich, Sheldon M. Wolff, and Charles A. Dinarello

Pillars Article: Nucleotide Sequence of Human Monocyte Interleukin 1 Precursor cDNA. Proc. Natl. Acad. Sci. USA. 1984. 81: 7907–7911

J Immunol 2007 178: 5413-5417 [PDF]


1985

Barry P. Sleckman and Eugene M. Oltz

Preparing Targets for V(D)J Recombinase: Transcription Paves the Way

J Immunol 2012 188: 7-9 [Full Text] [PDF]

George D. Yancopoulos and Frederick W. Alt

Pillars Article: Developmentally Controlled and Tissue-Specific Expression of Unrearranged VH Gene Segments. Cell. 1985. 40: 271–281

J Immunol 2012 188: 10-20 [PDF]


Jan Vilcek

First Demonstration of the Role of TNF in the Pathogenesis of Disease

J Immunol 2008 181: 5-6 [Full Text] [PDF]

Bruce Beutler, Ian W. Milsark, and Anthony C. Cerami

Pillars Article: Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin. Science. 1985. 229:869–871

J Immunol 2008 181: 7-9 [PDF]


Juan Carlos Zúñiga-Pflücker

The Original Intrathymic Progenitor from Which T Cells Originate

J Immunol 2009 183: 3-4 [Full Text] [PDF]

B. J. Fowlkes, Linette Edison, Bonnie J. Mathieson, and Thomas M. Chused

Pillars Article: Early T Lymphocytes. Differentiation In Vivo of Adult Intrathymic Precursor Cells. J. Exp. Med. 1985. 162: 802–822

J Immunol 2009 183: 5-25 [PDF]


Toshiaki Kawakami

A Crucial Door to the Mast Cell Mystery Knocked In

J Immunol 2009 183: 6861-6862 [Full Text] [PDF]

Toru Nakano, Takashi Sonoda, Chieko Hayashi, Atsushi Yamatodani, Yoshio Kanayama, Tei-Ichi Yamamura, Hidekazu Asai, Takeshi Yonezawa, Yukihiko Kitamura, and Stephen J. Galli

Pillars Article: Fate of Bone Marrow-Derived Cultured Mast Cells after Intracutaneous, Intraperitoneal, and Intravenous Transfer into Genetically Mast Cell-Deficient W/Wv Mice. Evidence That Cultured Mast Cells Can Give Rise to Both Connective Tissue Type and Mucosal Mast Cells. J. Exp. Med. 1985. 162: 1025–1043

J Immunol 2009 183: 6863-6881 [PDF]


Janice S. Blum

One for One Peptide Binding to MHC Molecules

J Immunol 2005 175: 4161-4162 [Full Text] [PDF]

Bruce P. Babbitt, Paul M. Allen, Gary Matsueda, Edgar Haber, and Emil R. Unanue

Pillars Article: Binding of Immunogenic Peptides to Ia Histocompatibility Molecules. Nature. 1985. 317: 359–361

J Immunol 2005 175: 4163-4165 [PDF]


1986

Lewis L. Lanier

Missing Self, NK Cells, and The White Album

J Immunol 2005 174: 6565-6565 [Full Text] [PDF]

Klas Kärre, Hans Gustaf Ljunggren, Gerald Piontek, and Rolf Kiessling

Pillars Article: Selective Rejection of H–2-Deficient Lymphoma Variants Suggests Alternative Immune Defence Strategy. Nature. 1986. 391: 675–678

J Immunol 2005 174: 6566-6569 [PDF]


Yvonne Paterson

When It Comes to CTL Recognition, Size Does Matter

J Immunol 2006 176: 5139-5140 [Full Text] [PDF]

A. R. M. Townsend, J. Rothbard, F. M. Gotch, G. Bahadur, D. Wraith, and A. J. McMichael

Pillars Article: The Epitopes of Influenza Nucleoprotein Recognized by Cytotoxic T Lymphocytes Can Be Defined with Short Synthetic Peptides. Cell. 1986. 44: 959–968

J Immunol 2006 176: 5141-5150 [PDF]


Jerry R. McGhee

The World of Th1/Th2 Subsets: First Proof

J Immunol 2005 175: 3-4 [Full Text] [PDF]

Timothy R. Mosmann, Holly Cherwinski, Martha W. Bond, Martin A. Giedlin, and Robert L. Coffman

Pillars Article: Two Types of Murine Helper T Cell Clone. I. Definition According to Profiles of Lymphokine Activities and Secreted Proteins. J. Immunol. 1986. 136: 2348–2357

J Immunol 2005 175: 5-14 [PDF]


Gail A. Bishop

The Power of Monoclonal Antibodies as Agents of Discovery: CD40 Revealed as a B Lymphocyte Costimulator

J Immunol 2012 188: 4127-4129 [Full Text] [PDF]

Edward A. Clark and Jeffrey A. Ledbetter

Pillars Article: Activation of Human B Cells Mediated through Two Distinct Cell Surface Differentiation Antigens, Bp35 and Bp50. Proc. Natl. Acad. Sci. USA. 1986. 83: 4494–4498

J Immunol 2012 188: 4130-4134 [PDF]


Eric O. Long

ICAM-1: Getting a Grip on Leukocyte Adhesion

J Immunol 2011 186: 5021-5023 [Full Text] [PDF]

Michael L. Dustin, Robert Rothlein, Atul K. Bhan, Charles A. Dinarello, and Timothy A. Springer

Pillars Article: Induction By IL 1 and Interferon-γ: Tissue Distribution, Biochemistry, and Function of a Natural Adherence Molecule (ICAM-1). J. Immunol. 1986. 137: 245–254

J Immunol 2011 186: 5024-5033 [PDF]

Robert Rothlein, Michael L. Dustin, Steven D. Marlin, and Timothy A. Springer

Pillars Article: A Human Intercellular Adhesion Molecule (ICAM-1) Distinct from LFA-1. J. Immunol. 1986. 137: 1270–1274

J Immunol 2011 186: 5034-5038 [PDF]


Martin Turner and Peter D. Katsikis

A New Mechanism of Gene Regulation Mediated by Noncoding RNA

J Immunol 2012 189: 3-4 [Full Text][PDF]

Gray Shaw and Robert Kamen

Pillars Article: A Conserved AU Sequence from the 3' Untranslated Region of GM-CSF mRNA MediatesSelective mRNA Degradation. Cell. 1986. 46: 659-667

J Immunol 2012 189: 5-13 [PDF]


Michael J. May

A Nuclear Factor in B Cells and Beyond

J Immunol 2006 177: 7483-7484 [Full Text] [PDF]

Ranjan Sen and David Baltimore

Pillars Article: Multiple Nuclear Factors Interact with the Immunoglobulin Enhancer Sequences. Cell. 1986. 46: 705–716

J Immunol 2006 177: 7485-7496 [PDF]


1987

Hélène Bour-Jordan and Jeffery A. Bluestone

How Suppressor Cells Led to Anergy, Costimulation, and Beyond

J Immunol 2009 183: 4147-4149 [Full Text] [PDF]

Marc K. Jenkins and Ronald H. Schwartz

Pillars Article: Antigen Presentation by Chemically Modified Splenocytes Induces Antigen-Specific T Cell Unresponsiveness In Vitro and In Vivo. J. Exp. Med. 1987. 165: 302–319

J Immunol 2009 183: 4150-4167 [PDF]


Jonathan Sprent

Proving Negative Selection in the Thymus

J Immunol 2005 174: 3841-3842 [Full Text] [PDF]

John W. Kappler, Neal Roehm, and Philippa Marrack

Pillars Article: T Cell Tolerance by Clonal Elimination in the Thymus Cell. 1987. 49: 273–280

J Immunol 2005 174: 3843-3850 [PDF]


Richard M. Ransohoff

Selective Leukocyte Chemoattractants Emerge from the Primeval Sup(ernatants)

J Immunol 2005 175: 5567-5568 [Full Text] [PDF]

Teizo Yoshimura, Kouji Matsushima, Joost J. Oppenheim, and Edward J. Leonard

Pillars Article: Neutrophil Chemotactic Factor Produced by Lipopolysaccharide(LPS)-Stimulated Human Blood Mononuclear Leukocytes: Partial Characterization and Separation from Interleukin 1 (IL 1). J. Immunol. 1987. 139: 788–793

J Immunol 2005 175: 5569-5574 [PDF]


Peter Parham

Putting a Face to MHC Restriction

J Immunol 2005 174: 3-5 [Full Text] [PDF]

P. J. Bjorkman, M. A. Saper, B. Samraoui, W. S. Bennett, J. L. Strominger, and D. C. Wiley

Pillars Article: Structure of the Human Class I Histocompatibility Antigen, HLA-A2. Nature. 1987. 329: 506–512

J Immunol 2005 174: 6-12 [PDF]

P. J. Bjorkman, M. A. Saper, B. Samraoui, W. S. Bennett, J. L. Strominger, and D. C. Wiley

Pillars Article: The Foreign Antigen Binding Site and T cell Recognition Regions of Class I Histocompatibility Antigens. Nature. 1987. 329: 512–518

J Immunol 2005 174: 13-19 [PDF]


Dario A. A. Vignali

CD4 on the Road to Coreceptor Status

J Immunol 2010 184: 5933-5934 [Full Text] [PDF]

Carolyn Doyle and Jack L. Strominger

Pillars Article: Interaction between CD4 and Class II MHC Molecules Mediates Cell Adhesion. Nature. 1987. 330: 256–259

J Immunol 2010 184: 5935-5938 [PDF]


1988

Mark Boothby

CRACking the Code without Rosetta: Molecular Regulation of Calcium-Stimulated Gene Transcription after T Cell Activation

J Immunol 2010 185: 4969-4971 [Full Text] [PDF]

Jeng-Pyng Shaw, Paul J. Utz, David B. Durand, J. Jay Toole, Elizabeth Ann Emmel, and Gerald R. Crabtree

Pillars Article: Identification of a Putative Regulator of Early T Cell Activation Genes. Science. 1988. 241: 202–205

J Immunol 2010 185: 4972-4975 [PDF]


Gary A. Koretzky

Multiple Roles of CD4 and CD8 in T Cell Activation

J Immunol 2010 185: 2643-2644 [Full Text][PDF]

Christopher E. Rudd, James M. Trevillyan, Jai Dev Dasgupta, Linda L. Wong, and Stuart F. Schlossman

Pillars Article: The CD4 Receptor Is Complexed in Detergent Lysates to a Protein-Tyrosine Kinase (Pp58) from Human T Lymphocytes. Proc. Natl. Acad. Sci. USA. 1988. 85: 5190–5194

J Immunol 2010 185: 2645-2649 [PDF]

André Veillette, Michael A. Bookman, Eva M. Horak, and Joseph B. Bolen

Pillars Article: The CD4 and CD8 T Cell Surface Antigens are Associated with the Internal Membrane Tyrosine-Protein Kinase p56lck. Cell. 1988. 55: 301–308

J Immunol 2010 185: 2650-2657 [PDF]


Jay A. Levy

The Unexpected Pleiotropic Activities of RANTES

J Immunol 2009 182: 3945-3946 [Full Text][PDF]

Thomas J. Schall, Jan Jongstra, Bradley J. Dyer, Jeffrey Jorgensen, Carol Clayberger, Mark M. Davis, and Alan M. Krensky

Pillars Article: A Human T Cell-Specific Molecule Is a Member of a New Gene Family. J. Immunol. 1988. 141: 1018–1025

J Immunol 2009 182: 3947-3954 [PDF]


Andrew Getahun, Shannon K. O'Neill, and John C. Cambier

Establishing Anergy as a Bona Fide In Vivo Mechanism of B Cell Tolerance

J Immunol 2009 183: 5439-5441 [Full Text][PDF]

Christopher C. Goodnow, Jeffrey Crosbie, Stephen Adelstein, Thomas B. Lavoie, Sandra J. Smith-Gill, Robert A. Brink, Helen Pritchard-Briscoe, John S. Wotherspoon, Robert H. Loblay, Kathy Raphael, Ronald J. Trent, and Antony Basten

Pillars Article: Altered Immunoglobulin Expression and Functional Silencing of Self-Reactive B Lymphocytes in Transgenic Mice. Nature. 1988. 334: 676–682

J Immunol 2009 183: 5442-5448 [PDF]


1989

Hidde L. Ploegh

The Peptide Cargo of Class I Molecules: Not Just Passive Passengers

J Immunol 2007 179: 4299-4300 [Full Text] [PDF]

Alain Townsend, Claes Öhlén, Judy Bastin, Hans-Gustaf Ljunggren, Linda Foster, and Klas Kärre

Pillars Article: Association of Class I Major Histocompatibility Heavy and Light Chains Induced by Viral Peptides. Nature. 1989. 340: 443–448

J Immunol 2007 179: 4301-4306 [PDF]


Janet Stavnezer and Joonsoo Kang

The Surprising Discovery That TGFβ Specifically Induces the IgA Class Switch

J Immunol 2009 182: 5-7 [Full Text] [PDF]

Robert L. Coffman, Deborah A. Lebman, and Barbara Shrader

Pillars Article: Transforming Growth Factor β Specifically Enhances IgA Production by Lipopolysaccharide-Stimulated Murine B Lymphocytes. J. Exp. Med. 1989. 170: 1039–1044

J Immunol 2009 182: 8-13 [PDF]

Eiichiro Sonoda, Ryoji Matsumoto, Yasumichi Hitoshi, Takehisa Ishii, Mineharu Sugimoto, Shukuro Araki, Akira Tominaga, Naoto Yamaguchi, and Kiyoshi Takatsu

Pillars Article: Transforming Growth Factor β Induces IgA Production and Acts Additively with Interleukin 5 for IgA Production. J. Exp. Med. 1989. 170: 1415–1420

J Immunol 2009 182: 14-19 [PDF]


Jack L. Strominger

An Alternative Path for Antigen Presentation: Group 1 CD1 Proteins

J Immunol 2010 184: 3303-3305 [Full Text] [PDF]

Steven Porcelli, Michael B. Brenner, Julia L. Greenstein, Cox Terhorst, Steven P. Balk, and Paul A. Bleicher

Pillars Article: Recognition of Cluster of Differentiation 1 Antigens by Human CD4CD8 Cytolytic T Lymphocytes. Nature. 1989. 341: 447–450

J Immunol 2010 184: 3306-3309 [PDF]


Vicky L. Brandt and David B. Roth

G.O.D.’s Holy Grail: Discovery of the RAG Proteins

J Immunol 2008 180: 3-4 [Full Text] [PDF]

David G. Schatz, Marjorie A. Oettinger, and David Baltimore

Pillars Article: The V(D)J Recombination Activating Gene, RAG-1. Cell. 1989. 59: 1035–1048

J Immunol 2008 180: 5-18 [PDF]


1990

James Hagman

Conveying the Message: Identification of Ig-α and Ig-β as Components of the B Cell Receptor Complex

J Immunol 2009 183: 1503-1504 [Full Text] [PDF]

Joachim Hombach, Takeshi Tsubata, LiseLeclercq, Heike Stappert, and Michael Reth

Pillars Article: Molecular Components of the B-cell Antigen Receptor Complex of the IgM Class. Nature. 1990. 243: 760–762

J Immunol 2009 183: 1505-1507 [PDF]


Harinder Singh

PU.1, a Shared Transcriptional Regulator of Innate and Adaptive Immune Cell Fates

J Immunol 2008 181: 1595-1596 [Full Text] [PDF]

Michael J. Klemsz, Scott R. McKercher, Antonio Celada, Charles Van Beveren, and Richard A. Maki

Pillars Article: The Macrophage and B Cell-Specific Transcription Factor PU.1 Is Related to the ets Oncogene. Cell. 1990. 61: 113–124

J Immunol 2008 181: 1597-1608 [PDF]


Michael J. Bevan

The Earliest Knockouts

J Immunol 2010 184: 4585-4586 [Full Text] [PDF]

Maarten Zijlstra, Mark Bix, Neil E. Simister, Janet M. Loring, David H. Raulet, and Rudolf Jaenisch

Pillars Article: β2-Microglobulin Deficient Mice Lack CD48+ Cytolytic T Cells. Nature. 1990. 344: 742–746

J Immunol 2010 184: 4587-4591 [PDF]

Beverly H. Koller, Philippa Marrack, John W. Kappler, and Oliver Smithies

Pillars Article: Normal Development of Mice Deficient in β2 M, MHC Class I Proteins, and CD8+ T Cells. Science. 1990. 248: 1227–1230

J Immunol 2010 184: 4592-4595 [PDF]


Kenneth M. Murphy

Cytokine Mimicry with an Immunologic Reformation: The Discovery of a Decade

J Immunol 2012 189: 2069-2071 [Full Text][PDF]

Kevin W. Moore, Paulo Vieira, David F. Fiorentino, Mary L. Trounstine, Tariq A. Khan, and Timothy R. Mosmann

Pillars Article: Homology of Cytokine Synthesis Inhibitory Factor (IL-10) to the Epstein-Barr Virus Gene BCRFI. Science. 1990. 248: 1230-1234

J Immunol 2012 189: 2072-2076 [PDF]


Yuwen Zhu and Lieping Chen

Turning the Tide of Lymphocyte Costimulation

J Immunol 2009 182: 2557-2558 [Full Text] [PDF]

Peter S. Linsley, Edward A. Clark, and Jeffrey A. Ledbetter

Pillars Article: T-Cell Antigen CD28 Mediates Adhesion with B Cells by Interacting with Activation Antigen B7/BB-1. Proc. Natl. Acad. Sci. USA. 1990. 87: 5031–5035

J Immunol 2009 182: 2559-2563 [PDF]


Melissa A. Brown

IL-4 Production by T Cells: You Need a Little to Get a Lot

J Immunol 2008 181: 2941-2942 [Full Text] [PDF]

Graham Le Gros, Shlomo Z. Ben-Sasson, Robert Seder, Fred D. Finkelman, and William E. Paul

Pillars Article: Generation of Interleukin 4 (IL-4)-producing Cells In Vivo and In Vitro: IL-2 and IL-4 Are Required For In Vitro Generation of IL-4-producing Cells. J. Exp. Med. 1990. 172: 921–929

J Immunol 2008 181: 2943-2951 [PDF]


Luc Van Kaer

Antigen Presentation: Discovery of the Peptide TAP

J Immunol 2008 180: 2723-2724 [Full Text] [PDF]

John J. Monaco, Sungae Cho, and Michelle Attaya

Pillars Article: Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing. Science. 1990. 250: 1723–1726

J Immunol 2008 180: 2725-2728 [PDF]

Edward V. Deverson, Irene R. Gow, W. John Coadwell, John J. Monaco, Geoffrey W. Butcher, and Jonathan C. Howard

Pillars Article: MHC Class II Region Encoding Proteins Related to the Multidrug Resistance Family of Transmembrane Transporters. Nature. 1990. 348: 738–741

J Immunol 2008 180: 2729-2732 [PDF]

John Trowsdale, Isabel Hanson, Ian Mockridge, Stephan Beck, Alain Townsend, and Adrian Kelly

Pillars Article: Sequences Encoded in the Class II Region of the MHC Related to the ‘ABC’ Superfamily of Transporters. Nature. 1990. 348: 741–744

J Immunol 2008 180: 2733-2736 [PDF]

Thomas Spies, Maureen Bresnahan, Seiamak Bahram, Daniele Arnold, George Blanck, Elizabeth Mellins, Donald Pious, and Robert DeMars

Pillars Article: A Gene in the Human Major Histocompatibility Complex Class II Region Controlling the Class I Antigen Presentation Pathway. Nature. 1990. 348: 744–747

J Immunol 2008 180: 2737-2740 [PDF]


1991

Judith A. Appleton

Costs and Benefits of Immunity to Worm Infection

J Immunol 2012 189: 1101-1103 [Full Text][PDF]

Edward J. Pearce, Patricia Caspar, Jean-Marie Grzych, Fred A. Lewis, and Alan Sher

Pillars Article: Downregulation of Th1 Cytokine Production Accompanies Induction of Th2 Responses by a Parasitic Helminth, Schistosoma mansoni. J. Exp. Med. 1991. 173: 159-166

J Immunol 2012 189: 1104-1111 [PDF]


Ronald N. Germain

Uncovering the Role of Invariant Chain in Controlling MHC Class II Antigen Capture

J Immunol 2011 187: 1073-1075 [Full Text] [PDF]

Paul A. Roche and Peter Cresswell

Pillars Article: Proteolysis of the Class II-Associated Invariant Chain Generates a Peptide Binding Site in Intracellular HLA-DR Molecules. Proc. Natl. Acad. Sci. USA. 1991. 88: 3150-3154

J Immunol 2011 187: 1076-1080 [PDF]


Paul W. Kincade

Moving the Field of B Lymphopoiesis

J Immunol 2012 189: 3269-3270 [Full Text][PDF]

Richard R. Hardy, Condie E. Carmack, Susan A. Shinton, John D. Kemp, and Kyoko Hayakawa

Pillars Article: Resolution and Characterization of Pro-B and Pre-Pro-B Cell Stages in Normal Mouse Bone Marrow. J. Exp. Med. 1991. 173:1213–1225

J Immunol 2012 189: 3271-3283 [PDF]


Linda A. Sherman

To Each (MHC Molecule) Its Own (Binding Motif)

J Immunol 2006 177: 2739-2740 [Full Text] [PDF]

Kirsten Falk, Olaf Rötzschke, Stefan Stevanovi, Günther Jung, and Hans-Georg Rammensee

Pillars Article: Allele-Specific Motifs Revealed by Sequencing of Self-Peptides Eluted from MHC Molecules. Nature. 1991. 351: 290–296

J Immunol 2006 177: 2741-2747 [PDF]


Emil R. Unanue

Altered Peptide Ligands Make Their Entry

J Immunol 2011 186: 7-8 [Full Text] [PDF]

Brian D. Evavold and Paul M. Allen

Pillars Article: Separation of IL-4 Production from Th Cell Proliferation by an Altered T Cell Receptor Ligand. Science. 1991. 252: 1308–1310

J Immunol 2011 186: 9-11 [PDF]


Barrett J. Rollins

Where the Confusion Began: Cloning the First Chemokine Receptors

J Immunol 2009 183: 2893-2894 [Full Text] [PDF]

William E. Holmes, James Lee, Wun-Jing Kuang, Glenn C. Rice, and William I. Wood

Pillars Article: Structure and Functional Expression of a Human Interleukin-8 Receptor. Science. 1991. 253: 1278–1280

J Immunol 2009 183: 2895-2897 [PDF]

Phillip M. Murphy and H. Lee Tiffany

Pillars Article: Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor. Science. 1991. 253: 1280–1283

J Immunol 2009 183: 2898-2901[PDF]


Olivera J. Finn

Human Tumor Immunology at the Molecular Divide

J Immunol 2007 178: 2615-2616 [Full Text] [PDF]

Pierre van der Bruggen, Catia Traversari, Patrick Chomez, Christophe Lurquin, Etienne De Plaen, Benoit J. Van den Eynde, Alexander Knuth, and Thierry Boon

Pillars Article: A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma. Science. 1991. 254: 1643–1647

J Immunol 2007 178: 2617-2621 [PDF]


1992

Lawrence J. Stern

Characterizing MHC-Associated Peptides by Mass Spectrometry

J Immunol 2007 179: 2667-2668 [Full Text] [PDF]

Donald F. Hunt, Robert A. Henderson, Jeffrey Shabanowitz, Kazuyasu Sakaguchi, Hanspeter Michel, Noelle Sevilir, Andrea L. Cox, Ettore Appella, and Victor H. Engelhard

Pillars Article: Characterization of Peptides Bound to the Class I MHC Molecule HLA-A2.1 by Mass Spectrometry. Science. 1992. 255: 1261–1263

J Immunol 2007 179: 2669-2671 [PDF]


Madhu Ramaswamy and Richard M. Siegel

Autoimmunity: Twenty Years in the Fas Lane

J Immunol 2012 189: 5097-5100 [Full Text][PDF]

Rie Watanabe-Fukunaga, Camilynn I. Brannan, Neal G. Copeland, Nancy A. Jenkins, and Shigekazu Nagata

Pillars Article: Lymphoproliferation Disorder in Mice Explained by Defects in Fas Antigen that Mediates Apoptosis. Nature. 1992. 356: 314–317

J Immunol 2012 189: 5101-5104 [PDF]


Thomas F. Tedder

Innate and Adaptive Receptors Interact to Balance Humoral Immunity

J Immunol 2010 184: 2231-2232 [Full Text] [PDF]

Robert H. Carter and Douglas T. Fearon

Pillars Article: CD19: Lowering the Threshold for Antigen Receptor Stimulation of B Lymphocytes. Science. 1992. 256: 105–107

J Immunol 2010 184: 2233-2235 [PDF]


Mary Ellen Conley and Peter D. Burrows

Plugging the Leaky Pre-B Cell Receptor

J Immunol 2010 184: 1127-1129 [Full Text] [PDF]

Daisuke Kitamura, Akira Kudo, Stefan Schaal, Werner Müller, Fritz Melchers, and Klaus Rajewsky

Pillars Article: A Critical Role of λ5 Protein in B Cell Development. Cell. 1992. 69: 823–831

J Immunol 2010 184: 1130-1138 [PDF]


Francisco Borrego

The First Molecular Basis of the "Missing Self" Hypothesis

J Immunol 2006 177: 5759-5760 [Full Text] [PDF]

Franz M. Karlhofer, Randall K. Ribaudo, and Wayne M. Yokoyama

Pillars Article: MHC Class I Alloantigen Specificity of Ly-49+ IL-2-Activated Natural Killer Cells. Nature. 1992. 358: 66–70

J Immunol 2006 177: 5761-5765 [PDF]


John J. O'Shea, Massimo Gadina, and Yuka Kanno

Cytokine Signaling: Birth of a Pathway

J Immunol 2011 187: 5475-5478 [Full Text] [PDF]

Laura Velazquez, Marc Fellous, George R. Stark, and Sandra Pellegrini

Pillars Article: A Protein Tyrosine Kinase in the Interferon α/β Signaling Pathway. Cell. 1992. 70: 313–322

J Immunol 2011 187: 5479-5488 [PDF]

Chris Schindler, Ke Shuai, Vincent R. Prezioso, and James E. Darnell, Jr.

Pillars Article: Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor. Science. 1992. 257: 809–813

J Immunol 2011 187: 5489-5494 [PDF]


1993

Wasif N. Khan

Colonel Bruton's Kinase Defined the Molecular Basis of X-Linked Agammaglobulinemia, the First Primary Immunodeficiency

J Immunol 2012 188: 2933-2935 [Full Text] [PDF]

Satoshi Tsukada, Douglas C. Saffran, David J. Rawlings, Ornella Parolini, R. Cutler Allen, Ivana Klisak, Robert S. Sparkes, Hiromi Kubagawa, Thuluvancheri Mohandas, Shirley Quan, John W. Belmont, Max D. Cooper, Mary Ellen Conley, and Owen N. Witte

Pillars Article: Deficient Expression of a B Cell Cytoplasmic Tyrosine Kinase in Human X-linked Agammaglobulinemia. Cell. 1993. 72: 279–290

J Immunol 2012 188: 2936-2947 [PDF]

David Vetrie, Igor Vořechovský, Paschalis Sideras, Jill Holland, Angela Davies, Frances Flinter, Lennart Hammarström, Christine Kinnon, Roland Levinsky, Martin Bobrow, C. I. Edvard Smith, and David R. Bentley

Pillars Article: The Gene Involved in X-linked Agammaglobulinaemia Is a Member of the Src Family of Protein-Tyrosine Kinases. Nature. 1993. 361: 226–233

J Immunol 2012 188: 2948-2955 [PDF]


Selvakumar Sukumar and Mark S. Schlissel

Receptor Editing as a Mechanism of B Cell Tolerance

J Immunol 2011 186: 1301-1302 [Full Text] [PDF]

Denise Gay, Thomas Saunders, Sally Camper, and Martin Weigert

Pillars Article: Receptor Editing: An Approach by Autoreactive B Cells to Escape Tolerance. J. Exp. Med. 1993. 177: 999–1008

J Immunol 2011 186: 1303-1312 [PDF]

Susan L. Tiegs, David M. Russell, and David Nemazee

Pillars Article: Receptor Editing in Self-reactive Bone Marrow B Cells. J. Exp. Med. 1993. 177: 1009–1020

J Immunol 2011 186: 1313-1324 [PDF]


Leslie J. Berg

The "Bubble Boy" Paradox: An Answer That Led to a Question

J Immunol 2008 181: 5815-5816 [Full Text] [PDF]

Masayuki Noguchi, Huafang Yi, Howard M. Rosenblatt, Alexandra H. Filipovich, Stephen Adelstein, William S. Modi, O. Wesley McBride, and Warren J. Leonard

Pillars Article: Interleukin-2 Receptor γChain Mutation Results in X-Linked Severe Combined Immunodeficiency in Humans. Cell. 1993. 73: 147–157

J Immunol 2008 181: 5817-5827 [PDF]


William E. Paul

Th1 Fate Determination in CD4+ T Cells: Notice Is Served of the Importance of IL-12!

J Immunol 2008 181: 4435-4436 [Full Text] [PDF]

Chyi-Song Hsieh, Steven E. Macatonia, Catherine S. Tripp, Stanley F. Wolf, Anne O'Garra, and Kenneth M. Murphy

Pillars Article: Development of TH 1 CD4+ T Cells Through IL-12 Produced by Listeria-Induced Macrophages. Science. 1993. 260: 547–549

J Immunol 2008 181: 4437-4439 [PDF]


Juan Carlos Zuniga-Pflucker

When Three Negatives Made a Positive Influence in Defining Four Early Steps in T Cell Development

J Immunol 2012 189: 4201-4202 [Full Text][PDF]

Dale I. Godfrey, Jacqueline Kennedy, Takashi Suda, and Albert Zlotnik

Pillars Article: A Developmental Pathway Involving Four Phenotypically and Functionally Distinct Subsets of CD3CD4CD8 Triple-Negative Adult Mouse Thymocytes Defined by CD44 and CD25 Expression. J. Immunol. 1993. 150: 4244-4252

J Immunol 2012 189: 4203-4211 [PDF]


Jeremy M. Boss

Controlling the Ir Genes

J Immunol 2007 178: 6675-6676 [Full Text][PDF]

Viktor Steimle, Luc A. Otten, Madeleine Zufferey, and Bernard Mach

Pillars Article: Complementation Cloning of an MHC Class II Transactivator Mutated in Hereditary MHC Class II Deficiency (or Bare Lymphocyte Syndrome). Cell. 1993. 75: 135–146

J Immunol 2007 178: 6677-6688 [PDF]


Kathrine E. Attfield and Lars Fugger

TCR Transgenic Mice That Shed Light on Immune and Environmental Regulators in Multiple Sclerosis

J Immunol 2013 190: 3015-3017 [Full Text][PDF]

Joan Goverman, Andrea Woods, Lisa Larson, Leslie P. Weiner, Leroy Hood, and Dennis M. Zaller

Pillars Article: Transgenic Mice that Express a Myelin Basic Protein-Specific T Cell Receptor Develop Spontaneous Autoimmunity. Cell. 1993. 72: 551–560

J Immunol 2013 190: 3018-3027 [PDF]

Juan J. Lafaille, Kumiko Nagashima, Motoya Katsuki, and Susumu Tonegawa

Pillars Article: High Incidence of Spontaneous Autoimmune Encephalomyelitis in Immunodeficient Anti-Myelin Basic Protein T Cell Receptor Transgenic Mice. Cell. 1994. 78: 399–408

J Immunol 2013 190: 3028-3037 [PDF]


1994

Stephen M. Hedrick

Positive Selection in the Thymus: An Enigma Wrapped in a Mystery

J Immunol 2012 188: 2043-2045 [Full Text] [PDF]

Kristin A. Hogquist, Stephen C. Jameson, William R. Heath, Jane L. Howard, Michael J. Bevan, and Francis R. Carbone

Pillars Article: T Cell Receptor Antagonist Peptides Induce Positive Selection. Cell. 1994. 76: 17–27

J Immunol 2012 188: 2046-2056 [PDF]


Kathryn Calame

Blimp-1’s Maiden Flight

J Immunol 2010 185: 3-4 [Full Text] [PDF]

C. Alexander Turner, Jr., David H. Mack, and Mark M. Davis

Pillars Article: Blimp-1, a Novel Zinc Finger-Containing Protein That Can Drive the Maturation of B Lymphocytes into Immunoglobulin-Secreting Cells. Cell. 1994. 77: 297–306

J Immunol 2010 185: 5-14 [PDF]


Hugh Auchincloss and Laurence A. Turka

CTLA-4: Not All Costimulation Is Stimulatory

J Immunol 2011 187: 3457-3458 [Full Text] [PDF]

Matthew F. Krummel and James P. Allison

Pillars Article: CD28 and CTLA-4 Have Opposing Effects on the Response of T Cells to Stimulation. J. Exp. Med. 1995. 182: 459–465

J Immunol 2011 187: 3459-3465 [PDF]

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker, Peter S. Linsley, Gordon J. Freeman, Jonathan M. Green, Craig B. Thompson, and Jeffrey A. Bluestone

Pillars Article: CTLA-4 Can Function as a Negative Regulator of T Cell Activation. Immunity. 1994. 1: 405–413

J Immunol 2011 187: 3466-3474 [PDF]


David L. Wiest

Identification of the Last Cog in a Ligand-Independent Signaling Machine?

J Immunol 2009 182: 5163-5164 [Full Text] [PDF]

Claude Saint-Ruf, Katharina Ungewiss, Marcus Groettrup, Ludovica Bruno, Hans Joerg Fehling, and Harald von Boehmer

Pillars Article: Analysis and Expression of a Cloned Pre-T Cell Receptor Gene. Science. 1994. 266: 1208–1212

J Immunol 2009 182: 5165-5169 [PDF]


1995

Tania H. Watts

Staying Alive: T Cell Costimulation, CD28, and Bcl-xL

J Immunol 2010 185: 3785-3787 [Full Text] [PDF]

Lawrence H. Boise, Andy J. Minn, Patricia J. Noel, Carl H. June, Mary Ann Accavitti, Tullia Lindsten, and Craig B. Thompson

Pillars Article: CD28 Costimulation Can Promote T Cell Survival by Enhancing the Expression of Bcl-xL. Immunity. 1995. 3: 87–98

J Immunol 2010 185: 3788-3799 [PDF]


Ethan M. Shevach

The Resurrection of T Cell-Mediated Suppression

J Immunol 2011 186: 3805-3807 [Full Text] [PDF]

Shimon Sakaguchi, Noriko Sakaguchi, Masanao Asano, Misako Itoh, and Masaaki Toda

Pillars Article: Immunologic Self-Tolerance Maintained by Activated T Cells Expressing IL-2 Receptor α-Chains(CD25). Breakdown of a Single Mechanism of Self-Tolerance Causes Various Autoimmune Diseases. J. Immunol. 1995. 155: 1151–1164

J Immunol 2011 186: 3808-3821 [PDF]


Sarah L. Gaffen

Life before Seventeen: Cloning of the IL-17 Receptor

J Immunol 2011 187: 4389-4391 [Full Text] [PDF]

Zhengbin Yao, William C. Fanslow, Michael F. Seldin, Anne-Marie Rousseau, Sally L. Painter, Michael R. Comeau, Jeffrey I. Cohen, and Melanie K. Spriggs

Pillars Article: Herpesvirus Saimiri Encodes a New Cytokine, IL-17, Which Binds to a Novel Cytokine Receptor. Immunity. 1995. 3: 811–821

J Immunol 2011 187: 4392-4402 [PDF]


1996

Robert W. Doms

Fusing HIV and Chemokine Receptors

J Immunol 2011 186: 6073-6075 [Full Text] [PDF]

Yu Feng, Christopher C. Brode, Paul E. Kennedy, and Edward A. Berger

Pillars Article: HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein–Coupled Receptor. Science. 1996. 272: 872–877

J Immunol 2011 186: 6076-6081 [PDF]


Daniel R. Goldstein

T Cell Costimulation Blockade and Organ Transplantation: A Change of Philosophy for Transplant Immunologists?

J Immunol 2011 186: 2691-2692 [Full Text] [PDF]

Christian P. Larsen, Eric T. Elwood, Diane Z. Alexander, Shannon C. Ritchie, Rose Hendrix, Carol Tucker-Burden, Hong Rae Cho, Alejandro Aruffo, Diane Hollenbaugh, Peter S. Linsley, Kevin J. Winn, and Thomas C. Pearson

Pillars Article: Long-Term Acceptance of Skin and Cardiac Allografts after Blocking CD40 and CD28 Pathways. Nature. 1996. 381: 434–438

J Immunol 2011 186: 2693-2697 [PDF]


Stefanie N. Vogel

How Discovery of Toll-Mediated Innate Immunity in Drosophila Impacted Our Understanding of TLR Signaling (and Vice Versa)

J Immunol 2012 188: 5207-5209 [Full Text] [PDF]

Bruno Lemaitre, Emmanuelle Nicolas, Lydia Michaut, Jean-Marc Reichhart, and Jules A. Hoffmann

Pillars Article: The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults. Cell. 1996. 86: 973-983

J Immunol 2012 188: 5210-5220 [PDF]


Peter C. Doherty

The Tetramer Transformation

J Immunol 2011 187: 5-6 [Full Text] [PDF]

John D. Altman, Paul A. H. Moss, Philip J. R. Goulder, Dan H. Barouch, Michael G. McHeyzer-Williams, John I. Bell, Andrew J. McMichael, and Mark M. Davis

Pillars Article: Phenotypic Analysis of Antigen-Specific T Lymphocytes. Science. 1996. 274: 94–96

J Immunol 2011 187: 7-9 [PDF]


Kai W. Wucherpfennig

The First Structures of T Cell Receptors Bound to Peptide–MHC

J Immunol 2010 185: 6391-6393 [Full Text] [PDF]

David N. Garboczi, Partho Ghosh, Ursula Utz, Qing R. Fan, William E. Biddison, and Don C. Wiley

Pillars Article: Structure of the Complex between Human T-Cell Receptor, Viral Peptide and HLA-A2. Nature. 1996. 384: 134–141

J Immunol 2010 185: 6394-6401 [PDF]

K. Christopher Garcia, Massimo Degano, Robyn L. Stanfield, Anders Brunmark, Michael R. Jackson, Per A. Peterson, Luc Teyton, and Ian A. Wilson

Pillars Article: An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex. Science. 1996. 274: 209–219

J Immunol 2010 185: 6402-6412 [PDF]


1997

Neil Warner and Gabriel Nunez

MyD88: A Critical Adaptor Protein in Innate Immunity Signal Transduction

J Immunol 2013 190: 3-4 [Full Text][PDF]

Holger Wesche, William J. Henzel, Wendy Shillinglaw, Shyun Li, and Zhaodan Cao

Pillars Article: MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex. Immunity. 1997. 7: 837–847

J Immunol 2013 190: 5-15 [PDF]

Marta Muzio, Jian Ni, Ping Feng, and Vishva M. Dixit

Pillars Article: IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling. Science. 1997. 278: 1612–1615

J Immunol 2013 190: 16-19 [PDF]

 


© The American Association of Immunologists, Inc.
9650 Rockville Pike | Bethesda, Maryland 20814 | Phone: (301) 634-7178 | Fax: (301) 634-7887
Email: infoaai@aai.org | Website feedback: AAI Webmaster